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ICGEB VOD

ICGEB VOD

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Course Insuline

  • Insulin
    • insulin 01-Insulin upstream
    • insulin 02-Sample Manipulation
    • insulin 03-Fermentor broth clarification
    • insulin 04-Insulin Precursor Purification
    • insulin 05-Transpeptidation of Insulin Precursor
    • insulin 06-Human insulin ester purification and crystallization
    • insulin 07-The deprotection reaction
    • 08-Human insulin purification and lyophilization

Course Detemir

  • Detemir
    • Detemir 01-Preparation of desB30-insulin
    • Detemir 02-Preparation of activated derivatives of Tetradecanoic (Myristic) acid
    • Detemir 03-Modification of DesB30-insulin with activated Myristic acid
    • Detemir 04-Detemir purification and crystallization

Course Degludec

  • Degludec
    • degludec 01-Preparation of desB30-insulin (degludec)
    • Degludec 02- Preparation of DEGLUDEC synthetic linker composed of hexadecanedioic acid and a gamma-L-glutamyl spacer
    • Degludec 03- Modification of DesB30-insulin with activated deprotected Degludec linker
    • Degludec 04- Chromatographic purification of Degludec from the reaction mixture
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